Extract from Cistus × Incanus L. Pandalis also Effective Against “British” Alpha (B.1.1.7) and “South African” Beta (B.1.351) SARS-CoV-2 Variants

Background: In previous studies, a special extract from Cistus × incanus L. Pandalis (Cystus Pandalis® extract) has already proven to be effective against SARS-CoV-2 in vitro. We assume that an effect was also likely the new variants, like “British” alpha variant (B.1.1.7) as well “South African” beta (B.1.351). Methods: To verify this, we investigated inhibition of cytopathic (CPE) coronaviruses by Cystus cell model with human intestinal cells (Caco-2). inoculated viral pre-treated herbal (A), and mixed viruses cultures (B). Result: observed almost complete virus growth at concentrations more than 100 μg/ml. The calculated IC50 (mean inhibitory concentration) for (B.1.351) is below 50 There no significant difference results two different ways treatment. Conclusion: Extract Cistus incanus Pandalis® can prevent in-vitro infections SARS-CoV-2. Due high vitro activity it appears reasonable future use prophylaxis A development resistance unlikely. People tolerate very well. It side effects.